Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp185 | Cell biology: osteoblasts and bone formation | ECTS2013

DNA-damage, survival, differentiation, and matrix mineralization in vitro of a murine multipotent mesenchymal precursor cell line

Lau Patrick , Hu Yueyuan , Hellweg Christine E , Baumstark-Khan Christa , Reitz Gunther

Radiation therapy is one of the most effective and indispensable treatment modalities for cancer patients. Known tissue complications caused by radiation-induced stem cell depletion, may result in structural and functional alterations of the surrounding matrix. Although, studies have demonstrated that ionizing radiation can induce apoptosis and senescence, little is known about the effects of therapeutic irradiation concerning the commitment of mesenchymal stem cells to the os...